Microdosing, a technique involving the administration of precise, minimal drug doses, can significantly accelerate the drug development process. By directly encapsulating drug substances into capsules, the powder-in-capsule (PIC) approach streamlines early-phase clinical trials. This method minimizes drug substance usage, eliminates the need for excipient compatibility studies, and simplifies analytical testing.
In the webinar Lonza experts explain how micro-dosing is leveraged as a cornerstone of the early-stage development strategy. By employing specialized equipment and expertise, the company efficiently transitions drug candidates from initial development to commercial-scale production. This streamlined approach enables rapid decision-making and accelerates the time to market for promising drug therapies.